That range is technically accurate but practically useless
Its also recommended to be cautious in people on certain medications like levodopa (without carbidopa), as mentioned, or those with specific medical conditions, but these are matters of caution rather than strict contraindications
When acetaminophen use was limited by a prescription requirement in the United States, the rate of autism was a small fraction of current rates of autism
CONTRAVE (naltrexone HCl and bupropion HCl), Extended-Release Tablets Label, Accessed October 10, 2023, Contrave (n.d.)
Solubility refers to the dissolution of the drug in an aqueous media, whereas permeability is the ability of a drug to cross membrane barriers and enter into the bloodstream