2,3 This guide covers what UK clinical guidance says about Mounjaro and pregnancy, what the current evidence shows, and how to plan stopping the medication if youre trying to conceive
doi: 10.1016/j.biopha.2021.111468 69 ZhangNLiuXZhuangLLiuXZhaoHShanYet al
Studies have shown that GLP-1R not only plays a role in regulating blood glucose, but is also involved in a variety of metabolic and non-metabolic processes, including inhibition of gastric emptying, appetite control, and improvement of cardiovascular function ( 3 Mechanism of action of GLP-1R in lowering blood glucose GLP-1R is expressed on pancreatic -cells, -cells and -cells and reduces blood glucose levels directly or indirectly (Figure 1A)
GLP-1 receptor activation also exerts cardioprotective effects, including improved endothelial function, reduced inflammation, and modest reductions in blood pressure and cholesterol levels
being at least 18 years of age