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We found that GLP-1 RA use was associated with a modestly higher incidence of psoriasis and lower incidences of pemphigus and bullous pemphigoid compared with DPP-4i use, while no increased risk was observed for most other autoimmune or inflammatory skin diseases
The genuine unknown is long-term effects in humans
The oral form, marketed as Wegovy, is specifically approved for chronic weight management in adults with obesity or overweight with at least one weight-related condition
The truth is more nuanced than headlines suggest: while the FDA has taken enforcement actions against certain manufacturers, compounded semaglutide from licensed 503A compounding pharmacies remains a legal, regulated treatment option available across all 50 states
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