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Puumala et al., 2024
It is contraindicated in patients with a history of brain cancer
The resulting hormonal shift naturally suppresses appetite for many patients
Figure from van der Aart-van der Beek AB, Nat Rev Nephrol, 2020 The Study Methods This was an international, event-driven, double-blind, parallel-group, randomized, placebo-controlled trial conducted at 387 sites in 28 countries comparing semaglutide to placebo in patients with T2DM and CKD, both being treated with baseline standard of care
One retrospective study 1 suggests comparable efficacy for both in Type 2 Diabetes
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