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Oral drugs undergo what is known as first-pass metabolism. First-pass metabolism is when the concentration of a drug, specifically when administered orally, is significantly reduced before it reaches systemic circulation
Biological sex: Women reach higher peak BAC than men from equivalent intake due to lower gastric ADH activity, lower body water percentage, and hormonal effects on ethanol absorption through the gastrointestinal tract
Benzyl alcohol is associated with Gasping Syndrome in newborns
Others notice steady improvement over several days
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