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The authors screened a pan-cancer tumor suppressor gene library using TGFB sensitivity as a phenotypic trait allowing for robust positive selection, and identified the transforming growth factor beta receptor 2 receptor ( TGFBR2 ) gene as a key mediator of CRC growth (Michels et al., 2020)
The Bottom Line Yesterday's advisory panel vote signals a shift in the regulatory landscape for peptide therapies, but it changes nothing for consumers today
World Journal of Gastroenterology, 23(5), 753-765.
Islam MR, et al
J Cell Biol 127(5):12451257
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