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Arylalkylamine N-acetyltransferase subsequently generates N-acetylserotonin that eventually becomes melatonin 1
95% CI: 0.19 to 0.38)
The primary endpoints were relative change in weight and the proportion of participants losing 5 or 10% of baseline weight at week 56
PMID: 15363638 Bremer J
Also appropriate if the constipation is significantly affecting quality of life or causing secondary symptoms like hemorrhoids or anal fissure from straining
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