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High-confidence substrates were identified by filtering for TMT-labeled neo-N termini significantly enriched in cells treated with active proteases compared to cells not treated with a protease or those treated with a catalytically inactive dead control

Front Nutr 10:1094081

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Rats in the HFD + ADF group exhibited markedly elevated levels of ALT, CK, and lactate, while levels of muscle glycogen and liver glycogen were significantly reduced

Indeed, it is the decline in GSH levels that has been associated with many chronic and age-related conditions, as well as the aging process itself