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While it has been in research for over 20 years, it has recently gained a second life thanks to the massive public interest in peptide therapy and the rise of GLP-1 medications.
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Synthetic peptides are engineered to improve bioavailability, target selectivity, and half-life, often surpassing the pharmacokinetic limitations of natural peptides. Vlieghe et al., Drug Discovery Today Do Natural and Synthetic Peptides Have Different Clearance Times
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