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L-tryptophan, an essential amino acid, converts to serotonin and melatonin in the body, further supports healthy sleep patterns

Derived from the roots of the Withania somnifera plant, it is a member of the nightshade family and is native to India and Asia

doi: 10.1016/j.prmcm.2025.100689

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The main limitations of that study included the small sample size, open-label design, and absence of concomitant rifaximin use, which is known to reduce short-term mortality