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High-dose oral therapy (10002000 micrograms daily) can be effective even in pernicious anaemia, as approximately 1% of B12 is absorbed through passive diffusion independent of intrinsic factor
1994 Dec;407:86-8
The finding shifted understanding of how mitochondria communicate beyond energy production, signaling through circulating peptides that reach distant tissues
The Journal of Nutrition, Volume 50, Issue 3, July 1953, Pages 331340, National Academy of Sciences
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