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129 Polymorphisms in SFTPA1 (rs1130142, rs713323, and rs1130143) and SFTPA2 (rs1130144) were suggested as possible genetic factors contributing to HAPE susceptibility, but the small sample size (12 HAPE patients and 15 controls) of the study limits its reliability
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247,248,249 Therefore, designing specific ligands to target this pathway can present therapeutic implications in asthma
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PMID: 252 SerranoDRLucianoFCAnayaBJOngorenBKaraAMolinaGet al
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