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Nat Rev Nephrol 10(2):88103 Lytvyn Y, Bjornstad P, van Raalte DH, Heerspink HL, Cherney DZI (2019) The new biology of diabetic kidney diseasemechanisms and therapeutic implications

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The central nervous system (CNS) depends almost exclusively on glucose to obtain energy, and the retina is part of the CNS

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Some research suggests this dual action may enhance weight loss effects compared to GLP-1 alone

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It is the smallest or second-smallest contributor

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