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IGF-1 LR3 vs IGF-1 DES vs HGH vs Mecasermin These four compounds all touch the GH/IGF-1 axis, but they act at different points and behave very differently

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For instance, in a randomised, placebo-controlled, double-blind Phase I study of ascending single doses of cotadutide in healthy individuals with overweight, there were dose-dependent improvements in glucose excursions post meal within 24 h and food intake reduction after a single dose of 100 g [82]

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