Adding in glucagon receptor agonist activity A clinically advanced molecule possessing glucagon receptor activity is the triple co-agonist retatrutide a single peptide molecule combining GLP-1, GIP and glucagon RA activity, delivered subcutaneously once weekly
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Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jdar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML
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GLP-1 Drugs Slow Down Progression of Chronic Kidney Disease Researchers examined long-term kidney outcomes with GLP-1 receptor agonist use compared with insulin in 11,634 patients treated with GLP-1 receptor agonists and 22,598 patients treated with insulin