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For a 20 mg vial, achieving 10 mg/mL concentration needs 2.0 mL of water
Time dependence refers to the pattern of side effects being most prominent during treatment initiation and dose increases, then declining as the body adapts
The BBB mechanism underlying water exchange (Kw) and Ktrans (related to contrast agent transfer) is likely to be different (Shao et al., 2020), since the first relates to permeability to water and the latter to GBCA
However, long-term studies specifically tracking extended use are lacking
His framing on where humans remain irreplaceable: You cant rely on AI to give you the answer on taste. The caveat: Ray Kurzweil put a shelf life on this consensus
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