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The proportion of new GLP-1 receptor agonist users with type 2 diabetes decreased during the study period in tandem with a twofold increase in the proportion of new users without type 2 diabetes and a BMI of 30 kg/m 2 or greater or a BMI between 27 kg/m 2 and 30 kg/m 2 and an obesity-related comorbid condition

This effect of GLP-1RAs may involve increased thermogenesis and modulation of mitochondrial function in various tissues

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