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Hepatic NF-B activity was determined by measuring both NF-B-DNA-binding activity using nuclear proteins and the expression of NF-B target genes
This was to form the stable nucleotide-free complex
It has also been shown that it can influence the proliferation and survival of cells and has a certain effect on the prognosis of some neoplastic diseases
Numerous other trials have demonstrated positive cardiovascular outcomes with focus on HFpEF in the SUMMIT trial for tirzepatide and the STEP-HFpEF trial for semaglutide [50,51,52]
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