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Here it is used along with antibiotics Excess acid production in the stomach caused by a growth in the pancreas (Zollinger-Ellison syndrome) Contraindications When should one not use Omeprazole If you have an allergic reaction to Omeprazole or other proton pump inhibitors Chronic heart failure Reduced calcium and magnesium levels Liver diseases If you are anti-HIV medications like Nelfinavir If you have or are suspected of having stomach cancer Side effects Common side effects of this drug are: Headache Constipation Diarrhea, stomach pain Nausea, vomiting Itching and rashes due to allergy Breathing difficulty Irregular heartbeat Fatigue Increased risk of infections on long term use Sleep disturbance Taste changes Low levels of sodium in the blood (rare) Joint pains (arthralgia) or muscle pains (myalgia) Hair loss (alopecia) (rare) Precautions and Warnings Pregnancy Breast Feeding Driving Alcohol Other General Warnings If you have liver issues You begin to vomit food or blood while taking this medicine or you pass black stools (blood-stained faeces) Severe diarrhea warning: it may increase your risk of severe diarrhea