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Photodecaging of a Mitochondria-localized iridium(III) endoperoxide complex for two-photon photoactivated therapy under hypoxia
This activation reduces the inhibitory binding between Caveolin-1 and eNOS, allowing greater eNOS activation and nitric oxide productionwith laboratory studies showing BPC-157 at 1 g/ml increases NO production 1.35-fold compared to controls
MillerRSWeaverLKBahrainiNChurchillSPriceRCSkibaVet al
R.CellmerT.DunkelbergerE
Also, BPC 157 may counteract cyclophosphamide toxicity (Luetic et al., 2017
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