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Jean-Pierre Raufman , working with biochemist John Eng , discovered that the Gila monster (a desert reptile) produces in its saliva a peptide that mimics GLP-1s action but is not rapidly destroyed by DPP-4 ( [45] ) ( [46] )

Batchuluun B, Inoguchi T, Sonoda N, Sasaki S, Inoue T, Fujimura Y, Miura D, Takayanagi R: Metformin and liraglutide ameliorate high glucose-induced oxidative stress via inhibition of PKC-NAD(P)H oxidase pathway in human aortic endothelial cells

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A three-amino-acid peptide of lysine, proline, and valine, taken from the C-terminal end of alpha-melanocyte-stimulating hormone (alpha-MSH)