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The company's own published disclosures acknowledge this classification
Because of tubular damage: Hypokalemia Hypomagnesemia Renal tubular acidosis (distal RTA) These electrolyte losses are often the earliest warning signs
The unique triple-agonist mechanism (GLP-1 + GIP + glucagon) has not produced unexpected safety signals beyond those anticipated from the individual receptor mechanisms
psychopharmacologyinstitute.com/section/can-gl
The GLP-1 receptor/GIP receptor/GCGR triple agonist efocipegtrutide is presently under investigation in individuals with MASLD, and preclinical accounts of other dual and triple agonists that include GLP-1 receptor and GCGR agonism suggest that clinical studies in individuals with type 2 diabetes will follow [62, 63]
