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Subcutaneous delivery supports controlled systemic exposure and predictable GH pulse activation in research protocols

[22] [23] Baseline assessment should be considered before initiating tirzepatide in high-risk patients, including those over 65 years of age, individuals with pre-existing gastrointestinal disorders, patients on concurrent metformin or acid-suppressing medications, and those following restrictive diets

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However, macronutrient profiles of what people ate remained the same before and after initiation of the drug

It is a synthetic peptide that acts as an analog of -melanocyte stimulating hormone (-MSH)