Conditions include alcoholic liver disease, viral hepatitis, cirrhosis, and primary or metastatic liver cancer Renal dysfunction : Impaired kidney function reduces B12 elimination, causing accumulation even with normal intake Haematological conditions : Myeloproliferative neoplasms, chronic myeloid leukaemia, polycythaemia vera, and hypereosinophilic syndrome increase transcobalamin production, elevating total serum B12 Laboratory interference : Macro-B12 (immunoglobulin-bound B12) and assay interference can cause spuriously elevated results without true excess In clinical practice, unexplained hypercobalaminaemia should prompt investigation for underlying disease, particularly in patients without obvious supplementation history
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These compounds can support the building blocks your body needs to preserve lean muscle mass, that may be helpful during periods of calorie restriction
Frequent alcohol consumption can lead to a deficiency in B12 and impact your Vitamin B12 levels by impairing your absorption of Vitamin B12, depleting your Vitamin B12 storage and promoting inadequate nutrition
