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However, despite advances in interventional techniques, patients with T2D still face a higher risk of adverse cardiovascular events and coronary lesion progression compared to non-diabetic patients 2

Available at: [accessed March 2026]. Reducing BMI below the obesity threshold in adolescents treated with once-weekly subcutaneous semaglutide 2.4 mg (STEP TEENS post hoc analysis)

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Documentation requirements are extensive: every compounded semaglutide prescription must include the patient's name, prescriber information, specific formulation details, lot numbers of ingredients used, pharmacist signature, and expiration dating

For practices and PCNs, the tirzepatide vs semaglutide question is best answered through eligibility, safety and pathway suitability rather than weight loss data alone