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GHK-Cu acts via dermal papilla stem cells and matrix

For this reason, several novel NBDHEX analogues, with improved selectivity for GSTP1-1, have been synthesized and characterized to obtain new therapeutic opportunities for the treatment of drug resistant tumors including human melanoma 100,101

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Subsequently, it was shown that IMC-A12 could decrease tumour growth in a transgenic mouse model of pancreatic neuroendocrine carcinogenesis when the IR level was decreased, demonstrating that the effect on tumour growth depends on the IR and IGF1R composition 25