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The NEJM Phase 2 trial documented stomach cramps on reta, stomach ache on reta, and lower-abdominal gas pain across all active-dose groups

(And the side effects arent minor nausea, vomiting, dehydration, constipation, and more serious risks like pancreatitis or kidney issues can all occur.) And because they don't closely monitor progress, they also don't initiate a change of plan or medication as the patient changes

Monoclonal antibodies and amyloid removal as a therapeutic strategy for cardiac amyloidosis

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Preclinical studies suggest GLP-1 agonists may reduce certain inflammatory markers, but these findings have not been validated in rheumatoid arthritis clinical trials