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In clinical trials, gastrointestinal adverse events were reported by a significant proportion of patients, though most were mild to moderate in severity and transient in nature

The NIH Clinical Trials registry lists two completed Phase II trials of ipamorelin for post-operative ileus (NCT00672269, NCT00820456), neither of which excluded SSRI-treated patients or reported interaction signals in safety analyses [16]

However, further research is warranted to establish this fact