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At pH 3.88 (acetate form), accelerated stability testing shows degradation to 21.3% remaining after extended heat stress, while at pH 8.42 (sodium salt), 96.7% remains under identical conditions
Potential Interactions with Other Medications One of the great things about B12 is that its a water-soluble vitamin, meaning your body simply excretes what it doesnt need
An intramuscular injection (commonly 1,000 mcg , given in the upper arm, hip or thigh) sidesteps the gut entirely and delivers a near-complete dose into circulation within minutes
This is especially important with compounded medications, which may have different stability profiles than their brand-name counterparts
Gluteal Muscle: Better for bigger shots, the gluteal is often used for Vitamin B12
