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It is produced through solid-phase peptide synthesis (SPPS) and supplied in lyophilized form for controlled laboratory use
No hGH Receptor Binding or IGF-1 Stimulation AOD9604 did not induce hyperglycaemia or reduce insulin secretion in sharp contrast to chronic intact hGH treatment and confirmed that the concept of hGH behaving as a pro-hormone is valid, with fragments capable of acting via mechanisms novel to traditional GH receptor-stimulated pathways
Like peptides, they are not approved for human use and are seen as experimental drugs with a risk of serious liver damage, thrombosis and heart problems
Structure [edit] The glutathione binding site, or "G-site", is located in the thioredoxin-like domain of both cytosolic and mitochondrial GSTs
