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J Intensive Care Med 2023;38(9):825-837
In 2006, Bruno et al
doi: 10.1080/10408398.2019.1604490 171
At least 70 enzymes have been identified as requiring CoA or ACP derivatives for their function including the same critical thiamine-dependent enzymes described above, the pyruvate dehydrogenase complex (PDHc), 2-oxoglutarate (-ketoglutarate) dehydrogenase complex (OGDH), and branched-chain -ketoacid dehydrogenase complex (BCKD)
As the smallest extracellular vesicles and endogenous source of nanocarriers, exosomes show great potential for cargo delivery, including RNA, protein, drugs, and ions
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