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Cagrilintide's phase 2 dose-finding trial randomised 706 adults over 26 weeks, and its phase 3 monotherapy data came from the REDEFINE 1 trial, which enrolled 3,417 adults over 68 weeks across all arms
In a small but critical subset, left arm symptoms accompany heart attack or strokemedical emergencies that need immediate attention
The peptides come and go while the GLP-1 therapy continues
This is the first demonstration to our knowledge of protection of hippocampal functions by oral administration of a hippocampus-based drug, suggesting that Hex may be explored for therapeutic intervention in AD
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