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Blue Cross Blue Shield of Massachusetts and Point32Health are discontinuing coverage of GLP-1 medications for weight loss, and CVS Caremark has restricted its formulary to Wegovy, removing Zepbound

Right now, there is no strong evidence that these probiotics meaningfully raise GLP-1 or lead to weight loss in humans

Value-based pricing considers the medications benefits to patients and the healthcare system, while cost-plus pricing adds a standard markup to the production costs

Assigned drug doses or vehicle (0.3% PBS, pH 8.0) were administered 3 h prior to the test session for all compounds tested

The primary outcome was the first occurrence of MACE, defined as death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke