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doi: 10.1111/j.1365-2044.1997.084-az0080.x
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Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein
More importantly, metformin treatment was shown to suppress senescence of mouse renal TECs under hyperglycemic condition (182)
When natural levels fall too low, cellular protection weakens, potentially contributing to health problems
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