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Satisfactory therapeutic effects were also observed with the combined use of olaparib and ABT-263 [137]
Reda A, Veys K, Kadam P, Taranta A, Rega LR, Goffredo BM, Camps C, Besouw M, Cyr D, Albersen M, Spiessens C, de Wever L, Hamer R, Janssen MCH, DHauwers K, Wetzels A, Monnens L, van den Heuvel L, Goossens E, Levtchenko E (2021) Human and animal fertility studies in cystinosis reveal signs of obstructive azoospermia, an altered blood-testis barrier and a subtherapeutic effect of cysteamine in testis
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Sulforaphane-rich cruciferous vegetables have been shown to modulate CYP3A4 activity and enhance aflatoxin B1 detoxification, which is particularly relevant for individuals with reduced-function CYP3A4 or GST/UGT variants.[ref][ref] On the conjugation side, phase II enzymes determine how quickly reactive mycotoxin intermediates are neutralized and excreted from the body
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