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Continuation beyond six months requires fresh specialist recommendation and a new HoD endorsement

Mechanisms differ from standard drugs

Undeclared active substances Swissmedic issues regular warnings about weight loss products that are allegedly entirely natural but which in reality contain undeclared, pharmacologically active substances

46 This study indicates several confounding factors influencing HbA1c reduction: baseline HbA1c, gender, and age, and also reports that ultimate BMI reduction was significantly associated with baseline HbA1c, baseline BMI and type of GLP-1 analogue

Reduced NEAT (non-exercise activity thermogenesis), hormonal shifts, water retention fluctuations, and changes in body composition all play roles