Novo's wildly popular weight-loss drug Wegovy has the same active ingredient
[6] [25] At levels only slightly below normal, deficiency can result in fatigue, headaches, feeling faint, rapid breathing, pale skin, numbness or tingling, poor appetite, heartburn, poor balance, difficulty walking, poor reflexes, blurred vision, memory problems, depression, irritability, inattention, cognitive decline, dementia, and even psychosis
The reason why it's important here: In contrast to the mu-opioid receptor and delta-opioid receptor agonists, KOR agonists are potent psychotomimetics in healthy people
For most, the weight returns quickly, typically within the first 3 to 6 months
Eli Lilly has not filed a New Drug Application with the FDA as of May 2026