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Across all simulations, semaglutide consistently generated positive incremental QALYs (minimum +0.03, maximum +0.10)
Animal studies identified thyroid C-cell tumours in rodents, but human relevance is unknown
Sleep quality: Weight loss and metabolic changes can sometimes temporarily disrupt sleep patterns, indirectly worsening daytime tiredness
Bone loss in the jaw, a common occurrence with missing teeth, can lead to a sunken facial appearance and further contribute to ill-fitting dentures
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