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Modeling Fitness of Unregulated RAS Mutants Using Computational Mutagenesis and Machine Learning, Majid Masso, Arnav Bansal, Akhil Gajjala, Preethi Prem, and Iosif Vaisman 45
Ther Adv Med Oncol
Further studies have suggested that DSIP may lead to increased secretion of growth hormone, positing that the peptide may potentially act on the hypothalamus to regulate hormonal secretion
These results indicate that downregulation of the PPARa pathway reduces FABP1 expression, leading to alterations in GPX4 and ACSL4 levels that contribute to HMC ferroptosis and IgAN pathogenesis [161]
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