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Laboratory studies using chondrocyte cultures and animal models have investigated how the peptide influences pathways involved in extracellular matrix regulation and tissue repair [4]
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4.6 Overcoming translational barriers: In Vivo stability and manufacturing hurdles Despite the immense preclinical promise of nanomedicine in osteosarcoma, several significant translational barriers must be addressed before clinical implementation (59, 68)
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GCL is composed of a catalytic (GCLC, Mr ~73 kDa) and a modifier (GCLM, Mr ~31 kDa) subunit [32] (summarized in Fig
