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Safety vs
Regeneration or Risk
Clinical research involving approximately 900 participants across six human trials specifically measured serum IGF-1 concentrations and found no changes with AOD-9604 treatment at doses up to 1 mg per day and beyond
The dosing regimen varies depending on whether neurological symptoms are present: With neurological involvement: 1 mg intramuscularly on alternate days until no further improvement, then 1 mg every 2 months [3] [4] Without neurological involvement: 1 mg intramuscularly three times a week for 2 weeks, then 1 mg every 2-3 months for maintenance [3] [4] There is some evidence that high-dose oral B12 (1000-2000 micrograms daily) may be effective even in some malabsorption conditions, though UK practice still generally favours intramuscular treatment in these cases
Practical result: Better visceral fat targeting during GLP-1 protocols, particularly in the later phases when the easy fat has already come off
