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Overall, in adults with type 1 diabetes and CKD, RAS inhibition reduces the risks of progression of microalbuminuria to macroalbuminuria by approximately 50% and of serum creatinine doubling by 2030% [21]
BMI thresholds, failed diet/behavioral programs) before allowing GLP-1 drugs ( [4] )
Insufficient Dosing and Tolerance Barriers Many people fail to reach an effective dose because they experience gastrointestinal side effects like nausea, constipation, or delayed gastric emptying during the titration phase
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