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The study comprised two cohorts: Cohort 1 included participants with negative SARS-CoV-2 RT-PCR test results on day 1, and Cohort 2 included participants with positive SARS-CoV-2 RT-PCR test results
7,8 Tumor heterogeneity, both spatial and temporal, adds another layer of complexity, as subclonal populations with distinct genetic and epigenetic features coexist and evolve under selective therapeutic pressure
Its important to note that despite these side effects, only a small proportion (8.1%) of the PT-141 group discontinued the medication
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