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For example, GLP-1 agonists have been shown to increase beneficial bacteria such as Bacteroides, Lactobacillus, and Bifidobacterium, while reducing inflammatory species with Enterobacteriaceae

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Combination approacheswhether through co-administration or unimolecular polypharmacologyare particularly attractive for underexplored peptides whose strengths lie in domains not fully addressed by current standards of care

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The approval came after extensive Phase 2 and Phase 3 clinical trials (HSDD) in premenopausal women