Lei G, Zhang Y, Koppula P et al (2020) The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression
Glutathione adverse effects and contraindications: The 2025 systematic review by Sarkar and Yadav explicitly noted that intravenous glutathione is contraindicated due to lack of efficacy evidence and adverse side effects
These observations allowed postulating that intracellular redox state of the thiol pool, which strongly depends on GSH level, can drive autophagic response at multiple levels (Filomeni et al., 2010)
Autism research is entering a new era
This leads to the cleavage and translocation of AIF from the mitochondrial intermembrane space to the nucleus, phosphorylation of the histone H2A family member H2AX, mitochondrial release of the death-inducing protein Smac/direct IAP-binding protein with low PI (DIABLO), and inhibition of the anti-apoptotic protein X-linked inhibitor of apoptosis (XIAP)