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How Much Weight Loss Do Clinical Trials Show: Retatrutide vs Tirzepatide Weight Management Research Data Phase 3 clinical trial data places retatrutides average body weight reduction at approximately 28% over 18 months, a figure that Eli Lilly and independent commentators have described as comparable to outcomes typically associated with bariatric surgery [2]
However, if youre getting B12 shots for general wellness, like improving energy or metabolism, its typically considered an elective treatment and paid for out-of-pocket
Pregnancy or breastfeeding: The safety of GLP-1s during pregnancy or while breastfeeding has not been fully established
In the United States, the FDA has also approved it to treat MASLD, a type of liver disease