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cerevisiae To better understand the genes involved in the GSH metabolism pathway in S.bacillaris, the genomes of the two previously sequenced ( The conventional GSH biosynthetic pathway (Figure 1) was evaluated by comparing S.bacillaris strains and S.cerevisiae EC1118/S288c in terms of enzymatic classes, localisation of genes across the genome (synteny), presence of transcriptional factors binding sites in promoter regions, and the putative effect of SNPs on GSH-related genes