Protamines Proteins that bind with DNA in sperm cells, replacing histones and allowing chromosomes to become more highly condensed than is possible with histones
Furthermore, in the context of polypharmacy, gastrointestinal side effects may have heightened clinical relevance, underscoring the importance of patient-based risk assessment in clinical practice
Hepatology 49 , 18771887 (2009)
In neurodegenerative disorders such as Alzheimers and Parkinsons diseases, alpha-lipoic acid has gained attention for its ability to reduce the accumulation of misfolded proteins within mitochondria (via mtUPR), as well as mitigate the excessive production of ROS, protecting neurons against mitochondrial dysfunction [75, 76]
Since Prx2 is a thiol-dependent peroxidase, it uses redox-active cysteines to reduce peroxides