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Deng et al., 2023)
This gives it a half-life long enough to support once-weekly dosing, a major practical advantage over earlier amylin-based therapies like pramlintide, which required multiple daily injections
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The angiogenesis data also applies to cardiovascular health
They disrupt fundamental cellular processes, including energy production, insulin signaling, glucose metabolism, and mitochondrial function, at times contributing to cognitive decline, fatigue, reduced ability to fight infections, and increased chronic disease risk
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