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The GHK motif itself occurs within the alpha-2(I) chain of type I collagen, so it is commonly classified as a matrikine, a fragment liberated during matrix degradation that signals back to the cells that deposited it

Access this article Similar content being viewed by others References Kim JC, Kim DD, Lee YM, et al

Elevated glutathione levels protected HepG2 cells not only from oxidative stress (generated by the redox cycler, paraquat) but also from mechanistically diverse stressors such as the inhibition of mitochondrial complex I by rotenone or the inhibition of the proteasomal system by MG-132 and bortezomib (Suppl